CDX1
CDX1 (Caudal type homeobox 1) هوَ بروتين يُشَفر بواسطة جين CDX1 في الإنسان.[1][2][3][4]
الوظيفة
هذا القسم فارغ أو غير مكتمل، ساهم بتحريره.
الأهمية السريرية
هذا القسم فارغ أو غير مكتمل، ساهم بتحريره.
المراجع
- Barker N, van Es JH, Kuipers J, Kujala P, van den Born M, Cozijnsen M, Haegebarth A, Korving J, Begthel H, Peters PJ, Clevers H (October 2007). "Identification of stem cells in small intestine and colon by marker gene Lgr5". Nature. 449 (7165): 1003–7. doi:10.1038/nature06196. PMID 17934449. الوسيط
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تم تجاهله (مساعدة) - "Entrez Gene: CDX1 caudal type homeobox transcription factor 1". مؤرشف من الأصل في 05 ديسمبر 2010. الوسيط
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تم تجاهله (مساعدة) - Grainger S, Hryniuk A, Lohnes D (2013). "Cdx1 and Cdx2 exhibit transcriptional specificity in the intestine". PLoS One. 8 (1): e54757. doi:10.1371/journal.pone.0054757. PMC 3559873. PMID 23382958. الوسيط
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تم تجاهله (مساعدة) - Bonner CA, Loftus SK, Wasmuth JJ (July 1995). "Isolation, characterization, and precise physical localization of human CDX1, a caudal-type homeobox gene". Genomics. 28 (2): 206–11. doi:10.1006/geno.1995.1132. PMID 8530027. الوسيط
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تم تجاهله (مساعدة)
قراءة متعمقة
- "Positional cloning of a gene involved in the pathogenesis of Treacher Collins syndrome. The Treacher Collins Syndrome Collaborative Group". Nature Genetics. 12 (2): 130–6. February 1996. doi:10.1038/ng0296-130. PMID 8563749. الوسيط
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تم تجاهله (مساعدة) - Mallo GV, Rechreche H, Frigerio JM, Rocha D, Zweibaum A, Lacasa M, Jordan BR, Dusetti NJ, Dagorn JC, Iovanna JL (February 1997). "Molecular cloning, sequencing and expression of the mRNA encoding human Cdx1 and Cdx2 homeobox. Down-regulation of Cdx1 and Cdx2 mRNA expression during colorectal carcinogenesis". International Journal of Cancer. 74 (1): 35–44. doi:10.1002/(SICI)1097-0215(19970220)74:1<35::AID-IJC7>3.0.CO;2-1. PMID 9036867. الوسيط
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تم تجاهله (مساعدة) - Mizoshita T, Inada K, Tsukamoto T, Kodera Y, Yamamura Y, Hirai T, Kato T, Joh T, Itoh M, Tatematsu M (2002). "Expression of Cdx1 and Cdx2 mRNAs and relevance of this expression to differentiation in human gastrointestinal mucosa--with special emphasis on participation in intestinal metaplasia of the human stomach". Gastric Cancer. 4 (4): 185–91. doi:10.1007/PL00011741. PMID 11846061. الوسيط
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تم تجاهله (مساعدة) - Suh ER, Ha CS, Rankin EB, Toyota M, Traber PG (September 2002). "DNA methylation down-regulates CDX1 gene expression in colorectal cancer cell lines". The Journal of Biological Chemistry. 277 (39): 35795–800. doi:10.1074/jbc.M205567200. PMID 12124393. الوسيط
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تم تجاهله (مساعدة) - Domon-Dell C, Schneider A, Moucadel V, Guerin E, Guenot D, Aguillon S, Duluc I, Martin E, Iovanna J, Launay JF, Duclos B, Chenard MP, Meyer C, Oudet P, Kedinger M, Gaub MP, Freund JN (September 2003). "Cdx1 homeobox gene during human colon cancer progression". Oncogene. 22 (39): 7913–21. doi:10.1038/sj.onc.1206756. PMID 12970739. الوسيط
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تم تجاهله (مساعدة) - Wong NA, Britton MP, Choi GS, Stanton TK, Bicknell DC, Wilding JL, Bodmer WF (January 2004). "Loss of CDX1 expression in colorectal carcinoma: promoter methylation, mutation, and loss of heterozygosity analyses of 37 cell lines". Proceedings of the National Academy of Sciences of the United States of America. 101 (2): 574–9. doi:10.1073/pnas.0307190101. PMC 327189. PMID 14704280. الوسيط
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تم تجاهله (مساعدة) - Rankin EB, Xu W, Silberg DG, Suh E (May 2004). "Putative intestine-specific enhancers located in 5' sequence of the CDX1 gene regulate CDX1 expression in the intestine". American Journal of Physiology. Gastrointestinal and Liver Physiology. 286 (5): G872-80. doi:10.1152/ajpgi.00326.2003. PMID 14715525. الوسيط
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تم تجاهله (مساعدة) - Béland M, Pilon N, Houle M, Oh K, Sylvestre JR, Prinos P, Lohnes D (June 2004). "Cdx1 autoregulation is governed by a novel Cdx1-LEF1 transcription complex". Molecular and Cellular Biology. 24 (11): 5028–38. doi:10.1128/MCB.24.11.5028-5038.2004. PMC 416402. PMID 15143193. الوسيط
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تم تجاهله (مساعدة) - Guo RJ, Huang E, Ezaki T, Patel N, Sinclair K, Wu J, Klein P, Suh ER, Lynch JP (August 2004). "Cdx1 inhibits human colon cancer cell proliferation by reducing beta-catenin/T-cell factor transcriptional activity". The Journal of Biological Chemistry. 279 (35): 36865–75. doi:10.1074/jbc.M405213200. PMID 15215241. الوسيط
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تم تجاهله (مساعدة) - Alkhoury F, Malo MS, Mozumder M, Mostafa G, Hodin RA (August 2005). "Differential regulation of intestinal alkaline phosphatase gene expression by Cdx1 and Cdx2". American Journal of Physiology. Gastrointestinal and Liver Physiology. 289 (2): G285-90. doi:10.1152/ajpgi.00037.2005. PMID 15774940. الوسيط
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تم تجاهله (مساعدة) - Wong NA, Wilding J, Bartlett S, Liu Y, Warren BF, Piris J, Maynard N, Marshall R, Bodmer WF (May 2005). "CDX1 is an important molecular mediator of Barrett's metaplasia". Proceedings of the National Academy of Sciences of the United States of America. 102 (21): 7565–70. doi:10.1073/pnas.0502031102. PMC 1140438. PMID 15894614. الوسيط
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تم تجاهله (مساعدة)
- بوابة طب
- بوابة علم الأحياء الخلوي والجزيئي
- بوابة الكيمياء الحيوية
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