TCF4
TCF4 (Transcription factor 4) هوَ بروتين يُشَفر بواسطة جين TCF4 في الإنسان.[1]
الوظيفة
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الأهمية السريرية
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المراجع
- Henthorn P, McCarrick-Walmsley R, Kadesch T (Feb 1990). "Sequence of the cDNA encoding ITF-2, a positive-acting transcription factor". Nucleic Acids Research. 18 (3): 678. doi:10.1093/nar/18.3.678. PMC 333500. PMID 2308860. مؤرشف من الأصل في 17 مايو 2020. الوسيط
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تم تجاهله (مساعدة)
قراءة متعمقة
- Herbst A, Helferich S, Behrens A, Göke B, Kolligs FT (Oct 2009). "The transcription factor ITF-2A induces cell cycle arrest via p21(Cip1)". Biochemical and Biophysical Research Communications. 387 (4): 736–40. doi:10.1016/j.bbrc.2009.07.102. PMID 19635457. الوسيط
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تم تجاهله (مساعدة) - Cisse B, Caton ML, Lehner M, Maeda T, Scheu S, Locksley R, Holmberg D, Zweier C, den Hollander NS, Kant SG, Holter W, Rauch A, Zhuang Y, Reizis B (Oct 2008). "Transcription factor E2-2 is an essential and specific regulator of plasmacytoid dendritic cell development". Cell. 135 (1): 37–48. doi:10.1016/j.cell.2008.09.016. PMC 2631034. PMID 18854153. الوسيط
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تم تجاهله (مساعدة) - Bain G, Murre C (Apr 1998). "The role of E-proteins in B- and T-lymphocyte development". Seminars in Immunology. 10 (2): 143–53. doi:10.1006/smim.1998.0116. PMID 9618760. الوسيط
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تم تجاهله (مساعدة) - Yerges LM, Klei L, Cauley JA, Roeder K, Kammerer CM, Moffett SP, et al. (Dec 2009). "High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men". Journal of Bone and Mineral Research. 24 (12): 2039–49. doi:10.1359/jbmr.090524. PMC 2791518. PMID 19453261. الوسيط
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تم تجاهله (مساعدة) - Purcell SM, Wray NR, Stone JL, Visscher PM, O'Donovan MC, Sullivan PF, Sklar P (Aug 2009). "Common polygenic variation contributes to risk of schizophrenia and bipolar disorder". Nature. 460 (7256): 748–52. doi:10.1038/nature08185. PMC 3912837. PMID 19571811. الوسيط
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تم تجاهله (مساعدة) - Kalscheuer VM, Feenstra I, Van Ravenswaaij-Arts CM, Smeets DF, Menzel C, Ullmann R, Musante L, Ropers HH (Aug 2008). "Disruption of the TCF4 gene in a girl with mental retardation but without the classical Pitt-Hopkins syndrome". American Journal of Medical Genetics Part A. 146A (16): 2053–9. doi:10.1002/ajmg.a.32419. PMID 18627065. الوسيط
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تم تجاهله (مساعدة) - Herbst A, Bommer GT, Kriegl L, Jung A, Behrens A, Csanadi E, et al. (Aug 2009). "ITF-2 is disrupted via allelic loss of chromosome 18q21, and ITF-2B expression is lost at the adenoma-carcinoma transition". Gastroenterology. 137 (2): 639–48, 648.e1-9. doi:10.1053/j.gastro.2009.04.049. PMID 19394332. الوسيط
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تم تجاهله (مساعدة) - Nagasawa M, Schmidlin H, Hazekamp MG, Schotte R, Blom B (Sep 2008). "Development of human plasmacytoid dendritic cells depends on the combined action of the basic helix-loop-helix factor E2-2 and the Ets factor Spi-B". European Journal of Immunology. 38 (9): 2389–400. doi:10.1002/eji.200838470. PMID 18792017. الوسيط
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تم تجاهله (مساعدة) - Rosenfeld JA, Leppig K, Ballif BC, Thiese H, Erdie-Lalena C, Bawle E, Sastry S, Spence JE, Bandholz A, Surti U, Zonana J, Keller K, Meschino W, Bejjani BA, Torchia BS, Shaffer LG (Nov 2009). "Genotype-phenotype analysis of TCF4 mutations causing Pitt-Hopkins syndrome shows increased seizure activity with missense mutations". Genetics in Medicine. 11 (11): 797–805. doi:10.1097/GIM.0b013e3181bd38a9. PMID 19938247. الوسيط
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تم تجاهله (مساعدة) - Stefansson H, Ophoff RA, Steinberg S, Andreassen OA, Cichon S, Rujescu D, et al. (Aug 2009). "Common variants conferring risk of schizophrenia". Nature. 460 (7256): 744–7. doi:10.1038/nature08186. PMC 3077530. PMID 19571808. الوسيط
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تم تجاهله (مساعدة)
- بوابة علم الأحياء الخلوي والجزيئي
- بوابة طب
- بوابة الكيمياء الحيوية
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