FGF7

FGF7
المعرفات
الأسماء المستعارة	FGF7, HBGF-7, KGF, fibroblast growth factor 7
معرفات خارجية	الوراثة المندلية البشرية عبر الإنترنت 148180 MGI: MGI:95521 HomoloGene: 7316 GeneCards: 2252
علم الوجود الجيني
الوظيفة الجزيئية	• heparin binding; • fibroblast growth factor receptor binding; • ‏GO:0001948 ربط بروتيني; • chemoattractant activity; • growth factor activity; • 1-phosphatidylinositol-3-kinase activity; • protein tyrosine kinase activity; • phosphatidylinositol-4,5-bisphosphate 3-kinase activity; • Ras guanyl-nucleotide exchange factor activity;
المكونات الخلوية	• جهاز غولجي; • منطقة خارج الخلية;
العمليات الحيوية	• actin cytoskeleton reorganization; • mesenchymal cell proliferation; • positive regulation of keratinocyte proliferation; • positive regulation of epithelial cell proliferation involved in lung morphogenesis; • secretion by lung epithelial cell involved in lung growth; • positive regulation of epithelial cell proliferation; • regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling; • MAPK cascade; • positive regulation of transcription, DNA-templated; • fibroblast growth factor receptor signaling pathway; • positive regulation of keratinocyte migration; • protein localization to cell surface; • response to wounding; • ضبط زيادي للتكاثر الخلوي; • epidermis development; • positive regulation of peptidyl-tyrosine phosphorylation; • hair follicle morphogenesis; • positive chemotaxis; • positive regulation of cell division; • توصيل الإشارة; • branching involved in salivary gland morphogenesis; • phosphatidylinositol phosphorylation; • peptidyl-tyrosine phosphorylation; • phosphatidylinositol-3-phosphate biosynthetic process; • regulation of receptor activity; • positive regulation of protein kinase B signaling;
	المصادر:Amigo / QuickGO
نمط التعبير عن الحمض النووي الريبوزي
	المزيد من بيانات التعبير المرجعية
أورثولوج
	P21781
	P36363
	NM_002009
	NM_008008
	NP_002000
	NP_032034
	ويكي بيانات
اعرض/عدّل إنسان	اعرض/عدّل فأر

FGF7‏ (Fibroblast growth factor 7) هوَ بروتين يُشَفر بواسطة جين FGF7 في الإنسان.[1][2][3]

الوظيفة

هذا القسم فارغ أو غير مكتمل، ساهم بتحريره.

الأهمية السريرية

هذا القسم فارغ أو غير مكتمل، ساهم بتحريره.

المراجع

"Entrez Gene: FGF7 fibroblast growth factor 7 (keratinocyte growth factor)". مؤرشف من الأصل في 05 ديسمبر 2010. الوسيط |CitationClass= تم تجاهله (مساعدة)
Kelley MJ, Pech M, Seuanez HN, Rubin JS, O'Brien SJ, Aaronson SA (Oct 1992). "Emergence of the keratinocyte growth factor multigene family during the great ape radiation". Proceedings of the National Academy of Sciences of the United States of America. 89 (19): 9287–91. doi:10.1073/pnas.89.19.9287. PMC 50111. PMID 1409637. الوسيط |CitationClass= تم تجاهله (مساعدة)
Mattei MG, deLapeyrière O, Bresnick J, Dickson C, Birnbaum D, Mason I (Mar 1995). "Mouse Fgf7 (fibroblast growth factor 7) and Fgf8 (fibroblast growth factor 8) genes map to chromosomes 2 and 19 respectively". Mammalian Genome. 6 (3): 196–7. doi:10.1007/BF00293012. PMID 7749227. الوسيط |CitationClass= تم تجاهله (مساعدة)

قراءة متعمقة

Beer HD, Gassmann MG, Munz B, Steiling H, Engelhardt F, Bleuel K, Werner S (Dec 2000). "Expression and function of keratinocyte growth factor and activin in skin morphogenesis and cutaneous wound repair". The Journal of Investigative Dermatology. Symposium Proceedings. 5 (1): 34–9. doi:10.1046/j.1087-0024.2000.00009.x. PMID 11147673. الوسيط |CitationClass= تم تجاهله (مساعدة)
Ware LB, Matthay MA (May 2002). "Keratinocyte and hepatocyte growth factors in the lung: roles in lung development, inflammation, and repair". American Journal of Physiology. Lung Cellular and Molecular Physiology. 282 (5): L924–40. doi:10.1152/ajplung.00439.2001. PMID 11943656. الوسيط |CitationClass= تم تجاهله (مساعدة)
Finch PW, Rubin JS (2004). "Keratinocyte growth factor/fibroblast growth factor 7, a homeostatic factor with therapeutic potential for epithelial protection and repair". Advances in Cancer Research. 91: 69–136. doi:10.1016/S0065-230X(04)91003-2. ISBN 978-0-12-006691-9. PMID 15327889. مؤرشف من الأصل في 07 ديسمبر 2019. الوسيط |CitationClass= تم تجاهله (مساعدة)
Ishibashi T, Bottaro DP, Chan A, Miki T, Aaronson SA (Dec 1992). "Expression cloning of a human dual-specificity phosphatase". Proceedings of the National Academy of Sciences of the United States of America. 89 (24): 12170–4. doi:10.1073/pnas.89.24.12170. PMC 50720. PMID 1281549. الوسيط |CitationClass= تم تجاهله (مساعدة)
Aaronson SA, Bottaro DP, Miki T, Ron D, Finch PW, Fleming TP, Ahn J, Taylor WG, Rubin JS (1992). "Keratinocyte growth factor. A fibroblast growth factor family member with unusual target cell specificity". Annals of the New York Academy of Sciences. 638: 62–77. doi:10.1111/j.1749-6632.1991.tb49018.x. PMID 1664700. الوسيط |CitationClass= تم تجاهله (مساعدة)
Finch PW, Rubin JS, Miki T, Ron D, Aaronson SA (Aug 1989). "Human KGF is FGF-related with properties of a paracrine effector of epithelial cell growth". Science. 245 (4919): 752–5. doi:10.1126/science.2475908. PMID 2475908. الوسيط |CitationClass= تم تجاهله (مساعدة)
Rubin JS, Osada H, Finch PW, Taylor WG, Rudikoff S, Aaronson SA (Feb 1989). "Purification and characterization of a newly identified growth factor specific for epithelial cells". Proceedings of the National Academy of Sciences of the United States of America. 86 (3): 802–6. doi:10.1073/pnas.86.3.802. PMC 286565. PMID 2915979. الوسيط |CitationClass= تم تجاهله (مساعدة)
Ron D, Reich R, Chedid M, Lengel C, Cohen OE, Chan AM, Neufeld G, Miki T, Tronick SR (Mar 1993). "Fibroblast growth factor receptor 4 is a high affinity receptor for both acidic and basic fibroblast growth factor but not for keratinocyte growth factor". The Journal of Biological Chemistry. 268 (8): 5388–94. PMID 7680645. الوسيط |CitationClass= تم تجاهله (مساعدة)
Yan G, Fukabori Y, McBride G, Nikolaropolous S, McKeehan WL (Aug 1993). "Exon switching and activation of stromal and embryonic fibroblast growth factor (FGF)-FGF receptor genes in prostate epithelial cells accompany stromal independence and malignancy". Molecular and Cellular Biology. 13 (8): 4513–22. PMC 360063. PMID 7687739. الوسيط |CitationClass= تم تجاهله (مساعدة)
Werner S, Smola H, Liao X, Longaker MT, Krieg T, Hofschneider PH, Williams LT (Nov 1994). "The function of KGF in morphogenesis of epithelium and reepithelialization of wounds". Science. 266 (5186): 819–22. doi:10.1126/science.7973639. PMID 7973639. الوسيط |CitationClass= تم تجاهله (مساعدة)
Wilson SE, Walker JW, Chwang EL, He YG (Jul 1993). "Hepatocyte growth factor, keratinocyte growth factor, their receptors, fibroblast growth factor receptor-2, and the cells of the cornea". Investigative Ophthalmology & Visual Science. 34 (8): 2544–61. PMID 8392040. الوسيط |CitationClass= تم تجاهله (مساعدة)
Guo L, Degenstein L, Fuchs E (Jan 1996). "Keratinocyte growth factor is required for hair development but not for wound healing". Genes & Development. 10 (2): 165–75. doi:10.1101/gad.10.2.165. PMID 8566750. الوسيط |CitationClass= تم تجاهله (مساعدة)
Ornitz DM, Xu J, Colvin JS, McEwen DG, MacArthur CA, Coulier F, Gao G, Goldfarb M (Jun 1996). "Receptor specificity of the fibroblast growth factor family". The Journal of Biological Chemistry. 271 (25): 15292–7. doi:10.1074/jbc.271.25.15292. PMID 8663044. الوسيط |CitationClass= تم تجاهله (مساعدة)
Post M, Souza P, Liu J, Tseu I, Wang J, Kuliszewski M, Tanswell AK (Oct 1996). "Keratinocyte growth factor and its receptor are involved in regulating early lung branching". Development. 122 (10): 3107–15. PMID 8898224. الوسيط |CitationClass= تم تجاهله (مساعدة)
Zimonjic DB, Kelley MJ, Rubin JS, Aaronson SA, Popescu NC (Oct 1997). "Fluorescence in situ hybridization analysis of keratinocyte growth factor gene amplification and dispersion in evolution of great apes and humans". Proceedings of the National Academy of Sciences of the United States of America. 94 (21): 11461–5. doi:10.1073/pnas.94.21.11461. PMC 23506. PMID 9326632. الوسيط |CitationClass= تم تجاهله (مساعدة)
Winkles JA, Alberts GF, Chedid M, Taylor WG, DeMartino S, Rubin JS (Dec 1997). "Differential expression of the keratinocyte growth factor (KGF) and KGF receptor genes in human vascular smooth muscle cells and arteries". Journal of Cellular Physiology. 173 (3): 380–6. doi:10.1002/(SICI)1097-4652(199712)173:3<380::AID-JCP10>3.0.CO;2-G. PMID 9369951. الوسيط |CitationClass= تم تجاهله (مساعدة)
Ishibashi T, Tanaka T, Nibu K, Ishimoto S, Kaga K (Oct 1998). "Keratinocyte growth factor and its receptor messenger RNA expression in nasal mucosa and nasal polyps". The Annals of Otology, Rhinology, and Laryngology. 107 (10 Pt 1): 885–90. PMID 9794620. الوسيط |CitationClass= تم تجاهله (مساعدة)
Mongiat M, Taylor K, Otto J, Aho S, Uitto J, Whitelock JM, Iozzo RV (Mar 2000). "The protein core of the proteoglycan perlecan binds specifically to fibroblast growth factor-7". The Journal of Biological Chemistry. 275 (10): 7095–100. doi:10.1074/jbc.275.10.7095. PMID 10702276. الوسيط |CitationClass= تم تجاهله (مساعدة)

بوابة الكيمياء الحيوية
بوابة طب
بوابة علم الأحياء الخلوي والجزيئي

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[entrez-1] "Entrez Gene: FGF7 fibroblast growth factor 7 (keratinocyte growth factor)". مؤرشف من الأصل في 05 ديسمبر 2010. الوسيط |CitationClass= تم تجاهله (مساعدة)

[pmid1409637-2] Kelley MJ, Pech M, Seuanez HN, Rubin JS, O'Brien SJ, Aaronson SA (Oct 1992). "Emergence of the keratinocyte growth factor multigene family during the great ape radiation". Proceedings of the National Academy of Sciences of the United States of America. 89 (19): 9287–91. doi:10.1073/pnas.89.19.9287. PMC 50111. PMID 1409637. الوسيط |CitationClass= تم تجاهله (مساعدة)

[pmid7749227-3] Mattei MG, deLapeyrière O, Bresnick J, Dickson C, Birnbaum D, Mason I (Mar 1995). "Mouse Fgf7 (fibroblast growth factor 7) and Fgf8 (fibroblast growth factor 8) genes map to chromosomes 2 and 19 respectively". Mammalian Genome. 6 (3): 196–7. doi:10.1007/BF00293012. PMID 7749227. الوسيط |CitationClass= تم تجاهله (مساعدة)